Yoav Gilad, PhD

The Gilad lab focuses on studying genetic and regulatory differences between humans and our close evolutionary relatives. Our long term goal is to identify the genetic basis of human-specific traits, including genetic variation that underlies higher susceptibility to certain diseases and disorders in humans than in other primates.

Weizmann Institute of Science
Rehovot, Israel
Ph.D. - Molecular Genetics
2003

Weizamnn Institute of Science
Rehovot, Israel
M.Sc. - Molecular Genetics
2000

Ben Gurion University
Beer-Sheva, Israel
B.Sc. - Molecular Genetics and Biochemistry
1998

Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons.
Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons. bioRxiv. 2023 Nov 20.
PMID: 37577666

Guided Differentiation of Pluripotent Stem Cells for Cardiac Cell Diversity.
Guided Differentiation of Pluripotent Stem Cells for Cardiac Cell Diversity. bioRxiv. 2023 Nov 17.
PMID: 37502898

Induced Pluripotent Stem Cells in Disease Biology and the Evidence for Their In Vitro Utility.
Induced Pluripotent Stem Cells in Disease Biology and the Evidence for Their In Vitro Utility. Annu Rev Genet. 2023 Nov 27; 57:341-360.
PMID: 37708421

The relationship between regulatory changes in cis and trans and the evolution of gene expression in humans and chimpanzees.
The relationship between regulatory changes in cis and trans and the evolution of gene expression in humans and chimpanzees. Genome Biol. 2023 09 11; 24(1):207.
PMID: 37697401

Evolutionary insights into primate skeletal gene regulation using a comparative cell culture model.
Evolutionary insights into primate skeletal gene regulation using a comparative cell culture model. PLoS Genet. 2022 03; 18(3):e1010073.
PMID: 35263340

Human embryoid bodies as a novel system for genomic studies of functionally diverse cell types.
Human embryoid bodies as a novel system for genomic studies of functionally diverse cell types. Elife. 2022 02 10; 11.
PMID: 35142607

Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation.
Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation. PLoS Genet. 2022 01; 18(1):e1009666.
PMID: 35061661

Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation.
Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation. Genome Biol. 2021 10 14; 22(1):291.
PMID: 34649612

Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions.
Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions. Elife. 2021 05 14; 10.
PMID: 33988505

Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees.
Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees. Elife. 2021 02 17; 10.
PMID: 33595436

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