Anna Di Rienzo, PhD

Research in our labs focuses on the genetic architecture of traits and diseases that vary across human populations and on understanding the role of natural selection in shaping this architecture. To this end, we use empirical population genetics and functional genomics approaches coupled with computational analyses of genome-scale data.

University of California
San Francisco, CA
- Human Molecular Genetics
1992

University of California
Berkeley, CA
- Human Population Genetics
1991

Institute of Cell Biology, National Research Council
Rome, Italy
- Human Molecular Genetics
1988

University of Rome La Sapienza
Rome, Italy
- Medical Genetics
1984

University of Rome La Sapienza
Rome, Italy
- Human Genetics
1980

A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans.
A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans. Sci Adv. 2022 Nov 25; 8(47):eade1942.
PMID: 36417539

Getting genetic ancestry right for science and society.
Getting genetic ancestry right for science and society. Science. 2022 04 15; 376(6590):250-252.
PMID: 35420968

Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors.
Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors. Nat Commun. 2022 03 08; 13(1):1203.
PMID: 35260549

Inferring the model and onset of natural selection under varying population size from the site frequency spectrum and haplotype structure.
Inferring the model and onset of natural selection under varying population size from the site frequency spectrum and haplotype structure. Proc Biol Sci. 2019 02 13; 286(1896):20182541.
PMID: 30963935

Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics.
Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):E11349-E11358.
PMID: 30429326

The genetic prehistory of the Andean highlands 7000 years BP though European contact.
The genetic prehistory of the Andean highlands 7000 years BP though European contact. Sci Adv. 2018 11; 4(11):eaau4921.
PMID: 30417096

Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal.
Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. PLoS Genet. 2018 09; 14(9):e1007650.
PMID: 30188897

The genomic landscape of Nepalese Tibeto-Burmans reveals new insights into the recent peopling of Southern Himalayas.
The genomic landscape of Nepalese Tibeto-Burmans reveals new insights into the recent peopling of Southern Himalayas. Sci Rep. 2017 Nov 14; 7(1):15512.
PMID: 29138459

Correction: A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau.
Correction: A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau. PLoS One. 2017; 12(8):e0183407.
PMID: 28797074

A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau.
A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau. PLoS One. 2017; 12(4):e0175885.
PMID: 28448508

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